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Axitinib

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Inlyta®
    • Brand Names: Canada: Inlyta®

    Uses
    • It is used to treat renal cancer.
    • Axitinib harms cancer cells causing their death.

    Dosing

    How to take

    • Take with or without food.
    • Swallow whole with a full glass of water.

    Missed Dose

    • Skip the missed dose and go back to your normal time.
    • If you throw up after taking a dose, skip dose and return to normal time.
    • Do not use 2 doses or extra doses.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • You may only get this drug from certain pharmacies.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

    Avoid

    • If you have an allergy to axitinib or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • If you have bleeding problems, talk with your doctor.
    • If you have had blood clots, talk with your doctor.
    • If you have had a recent heart attack, talk with your doctor.
    • If you have high blood pressure, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you are having surgery, talk with your doctor.
    • If you have thyroid disease, talk with your doctor.
    • Have your blood pressure checked often. Talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Have your urine checked. Talk with your doctor.
    • If you are taking a blood thinner, have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not take St John's wort with this drug. This drug may not work as well.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
    • Talk with your doctor before using products that have aspirin, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain drugs, or vitamin E.
    • Avoid grapefruit and grapefruit juice.
    • Use birth control that you can trust to stop pregnancy while taking this drug.
    • If you are a man and have sex, protect your partner from pregnancy. Use birth control that you can trust.

    Side Effects

    • Anemia, low white blood cell count, and low platelet count.
    • Loose stools (diarrhea).
    • Feeling tired or weak.
    • High blood pressure.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Weight loss.
    • Not hungry.
    • Redness or irritation of the palms of hands or soles of feet.
    • Mouth irritation.
    • High blood sugar.
    • Hard stools (constipation).
    • Muscle pain.
    • Cough.
    • Holes in the GI (gastrointestinal) tract may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Change in thinking clearly and with logic.
    • Sudden change in eyesight.
    • A fast heartbeat.
    • Chest pain or pressure.
    • Trouble breathing.
    • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
    • Very bad headache.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea).
    • Very hard stools (constipation).
    • Very bad swelling or pain of hands or feet.
    • Any bruising or bleeding.
    • Feeling very tired or weak.
    • Not able to handle heat or cold.
    • A big weight gain or loss.
    • Numbness or tingling in your hands or feet.
    • Very bad muscle pain.
    • Skin wound that will not heal.
    • Seizures.
    • Dark urine or yellow skin or eyes.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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